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Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
For Your Every Summer RSVP, with Code: SUMMER15
Description
Terminal Deoxynucleotidyl Transferase (TdT) Recombinant Rabbit mAb (S-R245)Product Specification Host Rabbit Antigen Terminal Deoxynucleotidyl Transferase (TdT) Synonyms DNA nucleotidylexotransferase, Terminal addition enzyme, DNTT Location Nucleus Accession P04053 Clone Number S R245 Antibody Type Recombinant mAb Application WB, ICC, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | Terminal Deoxynucleotidyl Transferase (TdT) |
| Synonyms | DNA nucleotidylexotransferase, Terminal addition enzyme, DNTT |
| Location | Nucleus |
| Accession | P04053 |
| Clone Number | S-R245 |
| Antibody Type | Recombinant mAb |
| Application | WB, ICC, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| ICC | 1:500 | null |
| IP | 1:50 | null |
Background
Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells. TdT adds N-nucleotides to the V, D, and J exons of the TCR and BCR genes during antibody gene recombination, enabling the phenomenon of junctional diversity. The diversity introduced by TdT has played an important role in the evolution of the vertebrate immune system, significantly increasing the variety of antigen receptors that a cell is equipped with to fight pathogens.
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