SKU: 47322875315

Carbonic Anhydrase IX/CA9 His Tag Protein, Cynomolgus

Sale price$162.00 Regular price$180.00
Save 10%

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 10 - Jul 15

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Carbonic Anhydrase IX/CA9 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms Carbonate dehydratase IX, Carbonic anhydrase IX (CA IX; CAIX), Membrane antigen MN, P54 58N Accession A0A2K5VQG9 Amino Acid Sequence Gln38 Leu398, with C terminal His Expression System HEK293 Molecular Weight 40 50 kDa (Reducing) Purity 95% by SDS PAGE &95% by SEC HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, pH7.

Product Specification


Species Cynomolgus
Synonyms Carbonate dehydratase IX, Carbonic anhydrase IX (CA-IX; CAIX), Membrane antigen MN, P54/58N
Accession A0A2K5VQG9
Amino Acid Sequence Gln38-Leu398, with C-terminal His
Expression System HEK293
Molecular Weight

40-50 kDa (Reducing)

Purity >95% by SDS-PAGE &>95% by SEC-HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, 5% trehalose, pH7.4,
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Reference

Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008; 7:168-81.
McDonald PC, Swayampakula M, Dedhar S. Coordinated regulation of metabolic transporters and migration/invasion by carbonic anhydrase IX. Metabolites 2018;8: E20.

Background

The CAIX works as a dimeric molecule composed of two monomeric proteins liked with a disulfide bond between cysteine residues of the two CAIX monomers, while the structure of CAXII is stabilized by 19 hydrogen-bonded interactions in the dimer interface. Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins that catalyze a very basic but crucial physiological reaction: the conversion of carbon dioxide into bicarbonate with a release of the proton. CAIX functions with bicarbonate transporters (including electroneutral bicarbonate transporter NBCn1 (SLC4A7)) to bring in HCO3- produced in a CAIX-mediated hydration reaction of CO2, and amino acid transporters (including the large neutral amino acid transporter 1 (LAT1) and CD98 heavy chain (CD98hc)) to transport in essential amino acids and glutamine (via interaction with glutamine transporter SLC1A5 and sodium-coupled neutral amino acid transporter 2 (SNAT2) facilitating the uptake of amino acid by SLC1A5), which cancer cells employ as an alternative metabolic energy source and biosynthetic precursor. CAIX also creates unique interactions with collagen- and laminin-binding integrins at the leading edge of migrating cells.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 47322875315

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.8 ★★★★★
Based on 1778 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
R
Verified Purchase
Ronald Bagley
Bozeman, US
★★★★★ 5
Wifi works great.
Style: WF-3820
Printer works great, learning curve to getting the settup right. Printed some pictures so fare nice prints and a lot of setings to ajust to give you exactly what your looking for.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 10, 2026
D
Verified Purchase
dee
Louisville, US
★★★★★ 5
All four functions
Style: WF-3820
Tested the fax. Copy. Print. Scan. They all work fine. There are other features it has but I didn't try yet. Not sure how fast it uses up the ink. I'm still using the ink it came with.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 21, 2026
A
Verified Purchase
Amazon Customer
Louisville, US
★★★★★ 5
Buena herramienta para impresión
Style: WF-3820
Buena impresora La recomiendo es rápida . Tiene algo que algunas veces toma dos hojas pero eso se resuelva con despegar las hojas
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2026
K
Verified Purchase
Katie Nieto
San Leandro, US
★★★★★ 5
I recommend it 100%.
Style: WF-3820, Style: WF-3820
I loved this product. I give it 5 stars because it is an excellent printer and copier; it works fast and has served me very well for both photos and documents. It is truly worth buying.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 1, 2026
A
Verified Purchase
Aury
Phoenix, US
★★★★★ 5
Easy and convenient to use
Love my product is easy to use, I truly recommend 100% price and quality.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026

recommand products